Price range: $268.00 through $328.00
Background:
kizuna centrosomal protein(KIZ) Homo sapiens The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013],
| Size | 50μL/100μL |
| Target | Kizuna |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 74kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 320-400 |
| Specificity | KIZ Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | PLK1S1 C20orf19 KIZ NCRNA00153 HT013 |
| Protein Name | Centrosomal protein kizuna (Polo-like kinase 1 substrate 1) |
| Other Name | Centrosomal protein kizuna; / Polo-like kinase 1 substrate 1 |
| Species | Human |
| Gene ID | 55857 |
| Uniprot | Q2M2Z5, |
| Species.1 | Mouse |
| Gene ID.1 | 228730 |
| Uniprot.1 | Q3UXL4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body . Localizes to centrosomes throughout the cell cycle. After centrosome duplication, it usually remains associated only with the mother centrosome, containing the older mature centriole and particles surrounding it. During prophase, additional particles accumulate around both separating centrosomes. Does not accumulate at the microtubule minus ends, but instead localizes to the centrosomes and centrosome-surrounding area in a microtubule-independent and dependent manner, respectively. . |
| Tissue Expression | Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | microtubule cytoskeleton organization, cytoskeleton organization, microtubule-based process, cell cycle, cell cycle process, microtubule organizing center organization, spindle pole body organization, |
