SKU: WP8560 Categories: ,

KLC3 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8560-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetKLC3
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)55kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human KLC3
SpecificityThis antibody detects endogenous levels of KLC3 at Human, Mouse,Rat
Gene NameKLC3 KLC2 KLC2L
Protein NameKinesin light chain 3 (KLC2-like) (kinesin light chain 2)
Other Name
SpeciesHuman
Gene ID147700
UniprotQ6P597,
Species.1Mouse
Gene ID.1232943
Uniprot.1Q91W40,
Species.2Rat
Gene ID.2171549
Uniprot.2Q68G30
Cellular LocalizationCytoplasm, cytoskeleton . Mitochondrion . In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria. Also localizes to the manchette in elongating spermatids. .
Tissue Expression
Signaling_pathwayHuman Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Research Areas
FunctionKinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa (By similarity). May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece (By similarity).
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