KLC3 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | KLC3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 55kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KLC3 |
| Specificity | This antibody detects endogenous levels of KLC3 at Human, Mouse,Rat |
| Gene Name | KLC3 KLC2 KLC2L |
| Protein Name | Kinesin light chain 3 (KLC2-like) (kinesin light chain 2) |
| Other Name | |
| Species | Human |
| Gene ID | 147700 |
| Uniprot | Q6P597, |
| Species.1 | Mouse |
| Gene ID.1 | 232943 |
| Uniprot.1 | Q91W40, |
| Species.2 | Rat |
| Gene ID.2 | 171549 |
| Uniprot.2 | Q68G30 |
| Cellular Localization | Cytoplasm, cytoskeleton . Mitochondrion . In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria. Also localizes to the manchette in elongating spermatids. . |
| Tissue Expression | |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases |
| Research Areas | |
| Function | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa (By similarity). May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece (By similarity). |
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