Product details
Background:
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KLF3 rabbit pAb
Ucallm_WP17449-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KLF3 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | 38kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KLF3 AA range: 51-101 |
| Specificity | This antibody detects endogenous levels of KLF3 at Human/Mouse |
| Gene Name | KLF3 BKLF |
| Protein Name | KLF3 |
| Other Name | |
| Species | Human |
| Gene ID | 51274 |
| Uniprot | P57682, |
| Species.1 | Mouse |
| Gene ID.1 | 16599 |
| Uniprot.1 | Q60980 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | |
| Signaling_pathway | Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer |
| Research Areas | >>Transcriptional misregulation in cancer |
| Function | Function:Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.,PTM:Sumoylated by SUMO1. Sumoylation is enhanced by PIAS1, PIAS2alpha and PIAS2beta, and PIAS4, but not by Pc2. Enhances transcriptional repression, but has no effect on DNA binding. Sumoylation on Lys-198 is the major site.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Monomer., |
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