Name: U-Blot® KLHL6 Rabbit mAb
SKU: WR4709
Price: 268 USD
Availability: InStock

U-Blot® KLHL6 Rabbit mAb

Western Blot analysis of K-562 whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-KLHL6 rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

WR4709 Western Blot analysis of K-562 whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-KLHL6 rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

Price range: $268.00 through $328.00

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SKU: WR4709-50

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Product details

Background:This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

Specifications

Target	KLHL6
Reactivity	Human
Applications	WB, IF, ICC, IP
MW(Calculated)
MW(Observed)	68kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:1000-5000; ICC/IF 1:100-300; IP 1:50-100
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	PT0796R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Sequence
Specificity	Endogenous
Gene Name	KLHL6
Protein Name	Kelch-like protein 6
Other Name	KLHL6; / Kelch-like protein 6
Species	Human
Gene ID-1	89857
Uniprot	Q8WZ60
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Cellular Localization
Tissue Expression	Found in germinal center B-cells. {ECO:0000269\|PubMed:12617994}.
Signaling_pathway
Research Areas
Function	Involved in B-lymphocyte antigen receptor signaling and germinal center formation. {ECO:0000250}.
RRID

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U-Blot® KLHL6 Rabbit mAb

Product details

Specifications

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U-Blot® KLHL6 Rabbit mAb

Product details

Specifications

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