KLRG1 rabbit pAb
Ucallm_WP7195-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | KLRG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 21kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KLRG1 |
| Specificity | This antibody detects endogenous levels of KLRG1 at Human, Mouse,Rat |
| Gene Name | KLRG1 CLEC15A MAFA MAFAL |
| Protein Name | Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen) |
| Other Name | |
| Species | Human |
| Gene ID | 10219 |
| Uniprot | Q96E93, |
| Species.1 | Mouse |
| Gene ID.1 | 50928 |
| Uniprot.1 | O88713, |
| Species.2 | Rat |
| Gene ID.2 | 58975 |
| Uniprot.2 | Q64335 |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein . |
| Tissue Expression | Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
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