Price range: $268.00 through $328.00
Background:
This is an intronless gene located in a cluster of related genes on the q arm of chromosome 21. The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins, thereby contributing to the structure and stability of hair fibers. [provided by RefSeq, Apr 2014],
| Size | 50μL/100μL |
| Target | KR104 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 44kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KR104 AA range: 349-399 |
| Specificity | This antibody detects endogenous levels of KR104 at Human |
| Gene Name | KRTAP10-4 KAP10.4 KAP18-4 KRTAP10.4 KRTAP18-4 KRTAP18.4 |
| Protein Name | KR104 |
| Other Name | |
| Species | Human |
| Gene ID | 386672 |
| Uniprot | P60372 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | keratin filament, |
| Tissue Expression | Restricted to hair root, not detected in any other tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 10 family.,subunit:Interacts with hair keratins.,tissue specificity:Restricted to hair root, not detected in any other tissues., |
