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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/KREM1 Polyclonal Antibody
SKU: WP2525 Categories: ,

KREM1 Polyclonal Antibody

Ucallm_WP2525-50

Price range: $268.00 through $328.00

SKU: WP2525-100
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Product details

Background:

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetKREM1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)52kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityKREM1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameKREMEN1 KREMEN KRM1
Protein NameKremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)
Other Name
SpeciesHuman
Gene ID83999
UniprotQ96MU8,
Species.1Mouse
Gene ID.1
Uniprot.1Q99N43,
Species.2Rat
Gene ID.2
Uniprot.2Q924S4
Cellular LocalizationCell membrane; Single-pass type I membrane protein .
Tissue ExpressionEye,
Signaling_pathway
Research Areas
FunctionFunction:Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling.,similarity:Contains 1 CUB domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 WSC domain.,
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