SKU: WP12961 Categories: ,

KV9.2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12961-100
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Product details

Background:

domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position., function:Potassium channel subunit. Modulates channel activity and reduces the ion flow., similarity:Belongs to the potassium channel family. S subfamily., subcellular location:May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1., subunit:Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins.,

Specifications

Size50μL/100μL
TargetKV9.2
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC
MW(Calculated)
MW(Observed)54kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human KCNS2. AA range:197-246
SpecificityKV9.2 Polyclonal Antibody detects endogenous levels of KV9.2 protein.
Gene NameKCNS2
Protein NamePotassium voltage-gated channel subfamily S member 2
Other NameKCNS2; / KIAA1144; / Potassium voltage-gated channel subfamily S member 2; / Delayed-rectifier K; / +; / channel alpha subunit 2; / Voltage-gated potassium channel subunit Kv9.2
SpeciesHuman
Gene ID3788
UniprotQ9ULS6,
Species.1Mouse
Gene ID.116539
Uniprot.1O35174,
Species.2Rat
Gene ID.266022
Uniprot.2Q9ER26
Cellular LocalizationCell membrane; Multi-pass membrane protein . May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2. .
Tissue ExpressionBrain,
Signaling_pathway
Research Areas
FunctionDomain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,Function:Potassium channel subunit. Modulates channel activity and reduces the ion flow.,similarity:Belongs to the potassium channel family. S subfamily.,subcellular location:May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.,subunit:Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins.,
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