Name: L-type Ca++ CP γ5 Polyclonal Antibody
SKU: WP5828
Price: 268 USD
Availability: InStock

L-type Ca++ CP γ5 Polyclonal Antibody

Ucallm_WP5828-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP5828-100

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Product details

Background:

calcium voltage-gated channel auxiliary subunit gamma 5(CACNG5) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010],

Specifications

Size	50μL/100μL
Target	L-type Ca++ CP γ5
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF
MW(Calculated)
MW(Observed)	35kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1000; IHC 1:100-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Polyclonal
Clone Number
Immunogen	Synthetic Peptide of L-type Ca++ CP γ5 AA range: 110-190
Specificity	The antibody detects endogenous L-type Ca++ CP γ5 protein.
Gene Name	CACNG5
Protein Name	Voltage-dependent calcium channel gamma-5 subunit
Other Name	CACNG5; / Voltage-dependent calcium channel gamma-5 subunit; / Neuronal voltage-gated calcium channel gamma-5 subunit; / Transmembrane AMPAR regulatory protein gamma-5; / TARP gamma-5
Species	Human
Gene ID	10369
Uniprot	Q9UF02,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q8VHW4,
Species.2	Rat
Gene ID.2
Uniprot.2	Q8VHW8
Cellular Localization	Membrane; Multi-pass membrane protein . Cell junction, synapse, postsynaptic density membrane .
Tissue Expression	Brain cortex,Thalamus,
Signaling_pathway	Organismal Systems >> Endocrine system >> Oxytocin signaling pathway;Organismal Systems >> Circulatory system >> Cardiac muscle contraction;Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Research Areas	>>MAPK signaling pathway; / >>Cardiac muscle contraction; / >>Adrenergic signaling in cardiomyocytes; / >>Oxytocin signaling pathway; / >>Hypertrophic cardiomyopathy; / >>Arrhythmogenic right ventricular cardiomyopathy; / >>Dilated cardiomyopathy
Function	Function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,

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L-type Ca++ CP γ5 Polyclonal Antibody

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L-type Ca++ CP γ5 Polyclonal Antibody

Product details

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