SKU: WP6671 Categories: ,

LANCL1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6671-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetLANCL1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)44kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human LANCL1
SpecificityThis antibody detects endogenous levels of LANCL1 at Human, Mouse,Rat
Gene NameLANCL1 GPR69A
Protein NameLanC-like protein 1 (40 kDa erythrocyte membrane protein) (p40)
Other Name
SpeciesHuman
Gene ID10314
UniprotO43813,
Species.1Mouse
Gene ID.114768
Uniprot.1O89112,
Species.2Rat
Gene ID.2114515
Uniprot.2Q9QX69
Cellular LocalizationCytoplasm . Cell membrane; Peripheral membrane protein .
Tissue ExpressionDetected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis.
Signaling_pathway
Research Areas
FunctionFunctions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism (By similarity). May play a role in EPS8 signaling. Binds glutathione .
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