Product details
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LAS1L rabbit pAb
Ucallm_WP7635-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | LAS1L |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 81kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human LAS1L |
| Specificity | This antibody detects endogenous levels of LAS1L at Human, Mouse |
| Gene Name | LAS1L MSTP060 |
| Protein Name | Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog) |
| Other Name | |
| Species | Human |
| Gene ID | 81887 |
| Uniprot | Q9Y4W2, |
| Species.1 | Mouse |
| Gene ID.1 | 76130 |
| Uniprot.1 | A2BE28 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. |
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