SKU: WP1023 Categories: ,

LC7L3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1023-100
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Product details

Background:

This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009],

Specifications

Size50μL/100μL
TargetLC7L3
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)47kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityLC7L3 Polyclonal Antibody detects endogenous levels of protein.
Gene NameLUC7L3 CREAP1 CROP O48
Protein NameLuc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)
Other Name
SpeciesHuman
Gene ID51747
UniprotO95232,
Species.1Mouse
Gene ID.1
Uniprot.1Q5SUF2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus speckle . The subnuclear localization is affected by cisplatin.
Tissue ExpressionWidely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.
Signaling_pathway
Research Areas
FunctionRNA processing, mRNA processing, apoptosis, cell death, RNA splicing, programmed cell death, mRNA metabolic process, death,
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