Price range: $268.00 through $328.00
Background:
Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | LDHC |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 170-250 |
| Specificity | LDHC Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | LDHC LDH3 LDHX |
| Protein Name | L-lactate dehydrogenase C chain (LDH-C) (Cancer/testis antigen 32) (CT32) (LDH testis subunit) (LDH-X) |
| Other Name | |
| Species | Human |
| Gene ID | 3948 |
| Uniprot | P07864, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P00342, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P19629 |
| Cellular Localization | Cytoplasm. |
| Tissue Expression | Brain,Testis, |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Glucagon signaling pathway;Human Diseases >> Cancer: overview >> Central carbon metabolism in cancer;Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway |
| Research Areas | >>Glycolysis / Gluconeogenesis; / >>Cysteine and methionine metabolism; / >>Pyruvate metabolism; / >>Propanoate metabolism; / >>Metabolic pathways; / >>HIF-1 signaling pathway; / >>Glucagon signaling pathway; / >>Central carbon metabolism in cancer |
| Function | Catalytic activity:(S)-lactate + NAD(+) = pyruvate + NADH.,Function:Possible role in sperm motility.,online information:Lactate dehydrogenase entry,pathway:Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.,similarity:Belongs to the LDH/MDH superfamily. LDH family.,subunit:Homotetramer., |
