LMTK1 Polyclonal Antibody
Ucallm_WP0556-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
Specifications
| Size | 50μL/100μL |
| Target | LMTK1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 151kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1110-1190 |
| Specificity | LMTK1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | AATK AATYK KIAA0641 LMR1 LMTK1 |
| Protein Name | Serine/threonine-protein kinase LMTK1 (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP) |
| Other Name | |
| Species | Human |
| Gene ID | 9625 |
| Uniprot | Q6ZMQ8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q80YE4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein . Cytoplasm . Cytoplasm, perinuclear region . Predominantly perinuclear. |
| Tissue Expression | Expressed in brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:May be involved in neuronal differentiation.,induction:Up-regulated during apoptosis.,PTM:Autophosphorylated. Phosphorylated by CDK5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly perinuclear.,subunit:Interacts with CDK5.,tissue specificity:Expressed in brain., |
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