Product details
Background:
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LMX1A rabbit pAb
Ucallm_WP17916-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | LMX1A |
| Reactivity | Human, Mouse |
| Applications | IHC, WB |
| MW(Calculated) | 42kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human N-ternal LMX1A |
| Specificity | This antibody detects endogenous levels of LMX1A at Human, Mouse |
| Gene Name | LMX1A |
| Protein Name | LIM homeobox transcription factor 1-alpha (LIM/homeobox protein 1.1) (LMX-1.1) (LIM/homeobox protein LMX1A) |
| Other Name | LIM homeobox transcription factor 1-alpha; / LIM/homeobox protein 1.1; / LMX-1.1; / LIM/homeobox protein LMX1A |
| Species | Human |
| Gene ID | 4009 |
| Uniprot | Q8TE12, |
| Species.1 | Mouse |
| Gene ID.1 | 110648 |
| Uniprot.1 | Q9JKU8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Isoform 1 is expressed in many tissues. Not found in heart, liver, spleen and testis. Relatively highly expressed in fetal brain. Isoform LMX1A-4AB is expressed in testis. |
| Signaling_pathway | |
| Research Areas | |
| Function | Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). |
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