SKU: WP5996 Categories: ,

LPCAT1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP5996-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetLPCAT1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)59kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human LPCAT1
SpecificityThis antibody detects endogenous levels of LPCAT1 at Human, Mouse,Rat
Gene NameLPCAT1 AYTL2 PFAAP3
Protein NameLysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3)
Other Name
SpeciesHuman
Gene ID79888
UniprotQ8NF37,
Species.1Mouse
Gene ID.1210992
Uniprot.1Q3TFD2,
Species.2Rat
Gene ID.2361467
Uniprot.2Q1HAQ0
Cellular LocalizationEndoplasmic reticulum membrane; Single-pass type II membrane protein . Golgi apparatus membrane; Single-pass type II membrane protein . Cell membrane; Single-pass type II membrane protein . Lipid droplet . May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm. .
Tissue ExpressionErythrocytes.
Signaling_pathway
Research Areas
FunctionExhibits acyltransferase activity . Exhibits acetyltransferase activity (By similarity). Activity is calcium-independent (By similarity). Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) . Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity). Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) (By similarity). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (By similarity). Involved in the regulation of lipid droplet number and size .
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