WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human LRC26 AA range: 163-213
Specificity
This antibody detects endogenous levels of LRC26 at Human/Mouse/Rat
Gene Name
LRRC26 CAPC
Protein Name
LRC26
Other Name
Species
Human
Gene ID
389816
Uniprot
Q2I0M4,
Species.1
Mouse
Gene ID.1
227618
Uniprot.1
Q91W20,
Species.2
Rat
Gene ID.2
311803
Uniprot.2
Q6P7C4
Cellular Localization
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Localizes to the cytoplasm when expressed at high levels. .
Tissue Expression
Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines.
Signaling_pathway
Research Areas
Function
similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Although predicted to be a single-pass type I membrane protein, this protein localizes to the cytoplasm when expressed at high levels (PubMed:15164053).,tissue specificity:Expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer.,