SKU: WR4714 Categories: ,

U-Blot® LYPD3 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR4714-50
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Product details

Background:Predicted to enable laminin binding activity. Involved in negative regulation of smooth muscle cell apoptotic process. Located in extracellular space. [provided by Alliance of Genome Resources, Feb 2025]

Specifications

Size50μL/100μL
TargetLYPD3
ReactivityHuman
ApplicationsWB, IHC, IP
MW(Calculated)
MW(Observed)38kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:1000-5000; IHC 1:100-300; IP 1:50-100 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM0801R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameLYPD3; C4.4A; UNQ491/PRO1007
Protein NameLy6/PLAUR domain-containing protein 3; GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein; MIG-C4
Other NameLYPD3; / C4.4A; / UNQ491/PRO1007; / Ly6/PLAUR domain-containing protein 3; / GPI-anchored metastasis-associated protein C4.4A homolog; / Matrigel-induced gene C4 protein; / MIG-C4
SpeciesHuman
Gene ID27076
UniprotO95274
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Lipid-anchor, GPI-anchor.
Tissue ExpressionExpressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. {ECO:0000269|PubMed:11179665, ECO:0000269|PubMed:12592373, ECO:0000269|PubMed:15012588}.
Signaling_pathway
Research Areas
FunctionSupports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression. {ECO:0000269|PubMed:11179665, ECO:0000269|PubMed:11245483, ECO:0000269|PubMed:12592373, ECO:0000269|PubMed:15012588}.
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