Product details
Background:
MACF1 rabbit pAb
Ucallm_WP4845-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MACF1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 813kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MACF1 AA range: 5623-5673 |
| Specificity | This antibody detects endogenous levels of human MACF1 |
| Gene Name | MACF1 ABP620 ACF7 KIAA0465 KIAA1251 |
| Protein Name | Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) |
| Other Name | |
| Species | Human |
| Gene ID | 23499 |
| Uniprot | Q9UPN3, |
| Species.1 | Mouse |
| Gene ID.1 | 11426 |
| Uniprot.1 | Q9QXZ0, |
| Species.2 | Rat |
| Gene ID.2 | 11426 |
| Uniprot.2 | D3ZHV2 |
| Cellular Localization | [Isoform 2]: Cytoplasm, cytoskeleton . Cytoplasm . Golgi apparatus . Cell membrane . Cell projection, ruffle membrane . The phosphorylated form is found in the cytoplasm while the non-phosphorylated form associates with the microtubules (By similarity). Localizes to the tips of microtubules (PubMed:27693509). Associated with the minus-end of microtubules via interaction with CAMSAP3 (PubMed:27693509). APC controls its localization to the cell membrane which is critical for its function in microtubule stabilization (PubMed:20937854). .; [Isoform 1]: Cytoplasm . Golgi apparatus . Localizes to the tips of microtubules. . |
| Tissue Expression | Isoform 2: Ubiquitously expressed. Isoform 1: Expressed in cell lines NCI-H460, A-549 and HaCaT. Isoform 4: Expressed in heart, lung, pituitary and placenta, not found in brain, kidney, liver, pancreas or skeletal muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function |
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