MAP-2 Monoclonal Antibody
Ucallm_WM0507-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],
Specifications
| Size | 50μL/100μL |
| Target | MAP-2 |
| Reactivity | Human, Mouse, Rat, Bovine, Pig |
| Applications | WB, IF |
| MW(Calculated) | 200kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-1:2000; IF 1:100-1:500; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 17G12 |
| Immunogen | Purified recombinant human MAP2 (N-terminus) protein fragments expressed in E.coli. |
| Specificity | MAP2 Monoclonal Antibody detects endogenous levels of MAP2 protein. |
| Gene Name | MAP2 |
| Protein Name | Microtubule-associated protein 2 |
| Other Name | MAP2; / Microtubule-associated protein 2; / MAP-2 |
| Species | Human |
| Gene ID | 4133 |
| Uniprot | P11137, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P20357, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P15146 |
| Cellular Localization | Cytoplasm, cytoskeleton . Cell projection, dendrite . |
| Tissue Expression | Brain,Brain cortex,Epithelium,Pancreas,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Alternative products:Additional isoforms seem to exist,Function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats., |
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