ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008],
Specifications
Size
50μL/100μL
Target
MAP-9
Reactivity
Human, Mouse
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
75kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
The antiserum was produced against synthesized peptide derived from human MAP9. AA range:121-170
Specificity
MAP-9 Polyclonal Antibody detects endogenous levels of MAP-9 protein.
Gene Name
MAP9
Protein Name
Microtubule-associated protein 9
Other Name
MAP9; / ASAP; / Microtubule-associated protein 9; / Aster-associated protein
Species
Human
Gene ID
79884
Uniprot
Q49MG5,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q3TRR0
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
Tissue Expression
Amygdala,Bone marrow,Brain,
Signaling_pathway
Research Areas
Function
developmental stage:Constitutively expressed during the cell cycle.,Function:Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.,subunit:Binds to purified microtubules via its C-terminus.,