Price range: $268.00 through $328.00
Background:
domain:The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity., function:Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation., PTM:O-glycosylated., similarity:Contains 1 SAP domain., similarity:Contains 3 RPEL repeats., subunit:Interacts with MKL1 and SRF.,
| Size | 50μL/100μL |
| Target | MKL2 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 119kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 500-580 |
| Specificity | MKL2 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | MKL2 KIAA1243 MRTFB |
| Protein Name | MKL/myocardin-like protein 2 (Megakaryoblastic leukemia 2) (Myocardin-related transcription factor B) (MRTF-B) |
| Other Name | |
| Species | Human |
| Gene ID | 57496 |
| Uniprot | Q9ULH7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P59759 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Amygdala,Brain,Cervix carcinoma,Epithelium,Medulla oblongata,Normal pituitary,Pancr |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity.,Function:Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.,PTM:O-glycosylated.,similarity:Contains 1 SAP domain.,similarity:Contains 3 RPEL repeats.,subunit:Interacts with MKL1 and SRF., |
