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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/MKP-7 Polyclonal Antibody
SKU: WP13183 Categories: ,

MKP-7 Polyclonal Antibody

Ucallm_WP13183-50

Price range: $268.00 through $328.00

SKU: WP13183-100
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Product details

Background:

dual specificity phosphatase 16(DUSP16) Homo sapiens This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010],

Specifications

Size50μL/100μL
TargetMKP-7
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)73kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human DUSP16. AA range:571-620
SpecificityMKP-7 Polyclonal Antibody detects endogenous levels of MKP-7 protein.
Gene NameDUSP16
Protein NameDual specificity protein phosphatase 16
Other NameDUSP16; / KIAA1700; / MKP7; / Dual specificity protein phosphatase 16; / Mitogen-activated protein kinase phosphatase 7; / MAP kinase phosphatase 7; / MKP-7
SpeciesHuman
Gene ID80824
UniprotQ9BY84
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
Tissue ExpressionBone marrow,Brain,Duodenum,PCR rescued clones,
Signaling_pathwayEnvironmental Information Processing >> Signal transduction >> MAPK signaling pathway
Research Areas>>MAPK signaling pathway
FunctionCatalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,Catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,Function:Involved in the inactivation of MAP kinases.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
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