SKU: WP3783 Categories: ,

MLEC rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3783-100
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Product details

Background:

This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Specifications

Size50μL/100μL
TargetMLEC
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)32kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human MLEC AA range: 165-215
SpecificityThis antibody detects endogenous levels of MLEC at Human/Mouse/Rat
Gene NameMLEC KIAA0152
Protein NameMLEC
Other Name
SpeciesHuman
Gene ID9761
UniprotQ14165,
Species.1Mouse
Gene ID.1109154
Uniprot.1Q6ZQI3,
Species.2Rat
Gene ID.2304543
Uniprot.2Q5FVQ4
Cellular LocalizationEndoplasmic reticulum membrane; Single-pass type I membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
FunctionFunction:Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation.,similarity:Belongs to the malectin family.,
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