MLEC rabbit pAb
Ucallm_WP3783-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Specifications
| Size | 50μL/100μL |
| Target | MLEC |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 32kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MLEC AA range: 165-215 |
| Specificity | This antibody detects endogenous levels of MLEC at Human/Mouse/Rat |
| Gene Name | MLEC KIAA0152 |
| Protein Name | MLEC |
| Other Name | |
| Species | Human |
| Gene ID | 9761 |
| Uniprot | Q14165, |
| Species.1 | Mouse |
| Gene ID.1 | 109154 |
| Uniprot.1 | Q6ZQI3, |
| Species.2 | Rat |
| Gene ID.2 | 304543 |
| Uniprot.2 | Q5FVQ4 |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation.,similarity:Belongs to the malectin family., |
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