Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human MMAB
Specificity
This antibody detects endogenous levels of MMAB at Human, Mouse
Gene Name
MMAB
Protein Name
Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B protein)
Other Name
Species
Human
Gene ID
326625
Uniprot
Q96EY8,
Species.1
Mouse
Gene ID.1
77697
Uniprot.1
Q9D273
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Mitochondrion .
Tissue Expression
Expressed in liver and skeletal muscle.
Signaling_pathway
Research Areas
Function
Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion . Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA (Probable).