Product details
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MMS2 rabbit pAb
Ucallm_WP7609-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | UBE2V2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 16kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MMS2 |
| Specificity | This antibody detects endogenous levels of MMS2 at Human, Mouse,Rat |
| Gene Name | UBE2V2 MMS2 UEV2 |
| Protein Name | Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein) |
| Other Name | |
| Species | Human |
| Gene ID | 7336 |
| Uniprot | Q15819, |
| Species.1 | Mouse |
| Gene ID.1 | 70620 |
| Uniprot.1 | Q9D2M8, |
| Species.2 | Rat |
| Gene ID.2 | 287927 |
| Uniprot.2 | Q7M767 |
| Cellular Localization | |
| Tissue Expression | Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. |
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