SKU: WP0773 Categories: ,

MOGT3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0773-100
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Product details

Background:

Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008],

Specifications

Size50μL/100μL
TargetMOGT3
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)37kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 10-90
SpecificityMOGT3 Polyclonal Antibody detects endogenous levels of protein.
Gene NameMOGAT3 DC7 DGAT2L7 UNQ9383/PRO34208
Protein Name2-acylglycerol O-acyltransferase 3 (Acyl-CoA:monoacylglycerol acyltransferase 3) (MGAT3) (Diacylglycerol O-acyltransferase candidate 7) (hDC7) (Diacylglycerol acyltransferase 2-like protein 7) (Monoacylglycerol O-acyltransferase 3)
Other Name
SpeciesHuman
Gene ID346606
UniprotQ86VF5
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein . Cytoplasm, perinuclear region .
Tissue ExpressionSelectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.
Signaling_pathway
Research Areas>>Glycerolipid metabolism; / >>Metabolic pathways; / >>Fat digestion and absorption
FunctionCatalytic activity:Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.,Catalytic activity:Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.,Function:Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.,pathway:Glycerolipid metabolism; triacylglycerol biosynthesis.,similarity:Belongs to the diacylglycerol acyltransferase family.,tissue specificity:Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.,
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