SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004],
Specifications
Size
50μL/100μL
Target
MOT10
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW(Calculated)
57kD
MW(Observed)
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human MOT10 AA range: 163-213
Specificity
This antibody detects endogenous levels of MOT10 at Human/Mouse/Rat
Gene Name
SLC16A10 MCT10 TAT1
Protein Name
MOT10
Other Name
Species
Human
Gene ID
117247
Uniprot
Q8TF71,
Species.1
Mouse
Gene ID.1
72472
Uniprot.1
Q3U9N9,
Species.2
Rat
Gene ID.2
170566
Uniprot.2
Q91Y77
Cellular Localization
Cell membrane; Multi-pass membrane protein . Basolateral cell membrane .
Tissue Expression
Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.
Signaling_pathway
Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway
Research Areas
>>Thyroid hormone signaling pathway; / >>Protein digestion and absorption
Function
Function:Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells.,PTM:Not N-glycosylated.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.,