SKU: WP1294 Categories: ,

MOT2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1294-100
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Product details

Background:

This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],

Specifications

Size50μL/100μL
TargetMOT2
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)52kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 220-300
SpecificityMOT2 Polyclonal Antibody detects endogenous levels of protein.
Gene NameSLC16A7 MCT2
Protein NameMonocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7)
Other Name
SpeciesHuman
Gene ID9194
UniprotO60669,
Species.1Mouse
Gene ID.1
Uniprot.1O70451,
Species.2Rat
Gene ID.2
Uniprot.2Q63344
Cellular LocalizationCell membrane; Multi-pass membrane protein .
Tissue ExpressionDetected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.
Signaling_pathway
Research Areas
Function
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