Nrf2 [PTR2557] mouse mAb
Ucallm_WM1271-50
Price range: $268.00 through $328.00
Product details
Background:
nuclear factor, erythroid 2 like 2(NFE2L2) Homo sapiens This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],
Specifications
| Size | 50μL/100μL |
| Target | Nrf2 |
| Reactivity | Human,Mouse,Rat, |
| Applications | WB,IF,ELISA |
| MW(Calculated) | 68kD |
| MW(Observed) | 100kD |
| Host Species | Mouse |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Protein G |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMMR2557 |
| Immunogen | Synthesized peptide derived from human Nrf2 AA range: 300-400 |
| Specificity | This antibody detects endogenous levels of Nrf2 protein. |
| Gene Name | NFE2L2 NRF2 |
| Protein Name | Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2) |
| Other Name | Nuclear factor erythroid 2-related factor 2;NF-E2-related factor 2;NFE2-related factor 2;HEBP1;Nuclear factor, erythroid derived 2, like 2; |
| Species | Human |
| Gene ID | 4780 |
| Uniprot | Q16236 |
| Species.1 | Mouse |
| Gene ID.1 | 18024 |
| Uniprot.1 | Q60795 |
| Species.2 | Rat |
| Gene ID.2 | 83619 |
| Uniprot.2 | O54968 |
| Cellular Localization | Cytoplasmic, Nuclear |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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