Nuclear protein [NeuN] [PTR1373]mouse mAb
Ucallm_WM1324-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
Specifications
| Size | 50μL/100μL |
| Target | NeuN |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 34kD |
| MW(Observed) | 46kD,48kD |
| Host Species | Mouse |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1000; WB 1:500-2000.IF 1:100-500.ELISA 1:1000-5000. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMMR1373 |
| Immunogen | Synthesized peptide derived from human protein. AA range:200-300 |
| Specificity | This antibody detects endogenous levels of Nuclear protein(NeuN) protein. |
| Gene Name | RBFOX3 |
| Protein Name | RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) |
| Other Name | RNA binding protein fox-1 homolog 3; / Fox-1 homolog C |
| Species | Human |
| Gene ID | 146713 |
| Uniprot | A6NFN3 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasmic, Nuclear |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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