U-Blot® ORP1 Rabbit mAb
Ucallm_WR4758-50
Price range: $268.00 through $328.00
Product details
Background:This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ORP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | 105kD |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1118R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1B |
| Protein Name | Oxysterol-binding protein-related protein 1 |
| Other Name | OSBL1; / Oxysterol-binding protein-related protein 1; / ORP-1; / OSBP-related protein 1 |
| Species | Human |
| Gene ID | 114876 |
| Uniprot | Q9BXW6, |
| Species.1 | Mouse |
| Gene ID.1 | 64291 |
| Uniprot.1 | Q91XL9, |
| Species.2 | Rat |
| Gene ID.2 | 259221 |
| Uniprot.2 | Q8K4M9 |
| Cellular Localization | Late endosome . Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes. |
| Tissue Expression | Bone,Brain,Embryo,Epithelium,Kidney,Pancreas,Testicle, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate.,similarity:Belongs to the OSBP family.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with VAPA., |
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