P27 Kip1 Mouse mAb [1A7]
Ucallm_WM1097-50
Price range: $268.00 through $328.00
Product details
Background:
Cyclin dependent kinase inhibitor 1B(CDKN1B) Homo sapiens This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Specifications
| Size | 50μL/100μL |
| Target | P27 Kip1 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, WB |
| MW(Calculated) | |
| MW(Observed) | 27kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC1:50-200; WB 1:1000-2000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Monoclonal |
| Clone Number | 1A7 |
| Immunogen | Synthesized peptide derived from human P27 Kip1 |
| Specificity | This antibody detects endogenous levels of P27 Kip1 at Human, Mouse,Rat |
| Gene Name | P27 Kip1 |
| Protein Name | P27 Kip1 |
| Other Name | |
| Species | Human |
| Gene ID | |
| Uniprot | P45627 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
Please login to post questions
Related products
