PEA3 Monoclonal Antibody
Product details
Background:
function:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5′[AC]GGA[AT]GT-3′., similarity:Belongs to the ETS family., similarity:Contains 1 ETS DNA-binding domain.,
Specifications
| Size | 50μL/100μL |
| Target | PEA3 |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | 54kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 20F11 |
| Immunogen | Purified recombinant fragment of human PEA3 (aa50-109) expressed in E. Coli. |
| Specificity | PEA3 Monoclonal Antibody detects endogenous levels of PEA3 protein. |
| Gene Name | ETV4 |
| Protein Name | ETS translocation variant 4 |
| Other Name | ETV4; / E1AF; / PEA3; / ETS translocation variant 4; / Adenovirus E1A enhancer-binding protein; / E1A-F; / Polyomavirus enhancer activator 3 homolog; / Protein PEA3 |
| Species | Human |
| Gene ID | 2118 |
| Uniprot | P43268, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P28322 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in keratinocytes. |
| Signaling_pathway | Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer |
| Research Areas | >>Transcriptional misregulation in cancer |
| Function | Function:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain., |
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