Price range: $268.00 through $328.00
Background:This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010],
| Size | 50μL/100μL |
| Target | Stra8 |
| Reactivity | Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 37kD |
| MW(Observed) | 50kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1391R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | STRA8 |
| Protein Name | Stimulated by retinoic acid gene 8 protein homolog |
| Other Name | STRA8; / Stimulated by retinoic acid gene 8 protein homolog |
| Species | Human |
| Gene ID | 346673 |
| Uniprot | Q7Z7C7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P70278 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Shuttles between nucleus and cytoplasm. Nuclear export is XPO1-dependent. . |
| Tissue Expression | Expressed specifically in testis and fetal ovaries. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.,PTM:Phosphorylated.,tissue specificity:Expressed specifically in testis., |
