Product details
Background:
RBM22 rabbit pAb
Ucallm_WP8588-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | RBM22 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 46kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RBM22 |
| Specificity | This antibody detects endogenous levels of RBM22 at Human, Mouse,Rat |
| Gene Name | RBM22 ZC3H16 199G4 |
| Protein Name | Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16) |
| Other Name | |
| Species | Human |
| Gene ID | 55696 |
| Uniprot | Q9NW64, |
| Species.1 | Mouse |
| Gene ID.1 | 66810 |
| Uniprot.1 | Q8BHS3, |
| Species.2 | Rat |
| Gene ID.2 | 307410 |
| Uniprot.2 | Q4V7D7 |
| Cellular Localization | Nucleus . Cytoplasm . Nearly exclusively nuclear. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Required for pre-mRNA splicing as component of the activated spliceosome . Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. |
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