SKU: WP6546 Categories: ,

RBM39 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6546-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetRBM39
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)58kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RBM39
SpecificityThis antibody detects endogenous levels of RBM39 at Human, Mouse
Gene NameRBM39 HCC1 RNPC2
Protein NameRNA-binding protein 39 (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Other Name
SpeciesHuman
Gene ID9584
UniprotQ14498,
Species.1Mouse
Gene ID.1170791
Uniprot.1Q8VH51
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus speckle . Concentrated in nuclear speckles (PubMed:8227358). Colocalizes with the core spliceosomal snRNP proteins (PubMed:8227358). .
Tissue ExpressionWidely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain (PubMed:8227358). Expressed at intermediate level in kidney, liver and heart (PubMed:8227358).
Signaling_pathway
Research Areas
FunctionRNA-binding protein that acts as a pre-mRNA splicing factor . Acts by promoting exon inclusion via regulation of exon cassette splicing . Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity (By similarity).
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