Recombinant CD134 Fc-Fused Nanobody (VF0315)
Ucallm_WN0078
$365.00
Product details
Background:CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.
Specifications
| Size | 100μL |
| Target | CD134 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000 |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0303 |
| Immunogen | Purified recombinant Human CD134 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD134 protein. |
| Gene Name | TNFRSF4 TXGP1L |
| Protein Name | Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134) |
| Other Name | ACT 35 antibody; / ACT35 antibody; / ACT35 antigen antibody; / ATC35 antigen antibody; / CD 134 antibody; / CD134 antibody; / CD134 antigen antibody; / IMD16 antibody; / Lymphoid activation antigene ACT35 antibody; / OX 40 antibody; / OX40 antibody; / OX40 antigen antibody; / OX40 cell surface antigen antibody; / OX40 homologue antibody; / OX40L receptor antibody; / TAX transcriptionally activated glycoprotein 1 receptor antibody; / TAX transcriptionally-activated glycoprotein 1 receptor antibody; / TNF receptor superfamily member 4 antibody; / TNFRSF 4 antibody; / TNFRSF4 antibody; / TNR4_HUMAN antibody; / Tumor necrosis factor receptor superfamily member 4 antibody; / Txgp 1l antibody; / Txgp1 antibody; / Txgp1l antibody |
| Species | Human |
| Gene ID | 7293 |
| Uniprot | P43489 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Expression | Expressed by activated B-lymphocytes and monocytes. |
| Signaling_pathway | Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction |
| Research Areas | |
| Function | Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B. |
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