Recombinant CD56 Fc-Fused Nanobody (VF0634)
Product details
Background:This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Specifications
| Size | 100μL |
| Target | CD56 |
| Reactivity | Human |
| Applications | ELISA, FC |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000; Flow Cyt 1-2μg/Test |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0502 |
| Immunogen | Purified recombinant Human CD56 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD56 protein. |
| Gene Name | NCAM1 NCAM |
| Protein Name | Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) |
| Other Name | antigen MSK39 identified by monoclonal 5.1H11; / antigen recognized by monoclonal 5.1H11; / CD56; / cell adhesion molecule; / neural; / 1; / MSK 39; / MSK39; / N-CAM-1; / NCAM 1; / NCAM; / NCAM C; / NCAM-1; / NCAM1; / NCAM1_HUMAN; / NCAMC; / Neural cell adhesion molecule 1; / Neural cell adhesion molecule NCAM; / OTTHUMP00000235666; / CD56 nanobody |
| Species | Human |
| Gene ID | 4684 |
| Uniprot | P13591 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 4]: Cell membrane; Lipid-anchor, GPI-anchor .; [Isoform 5]: Secreted.; [Isoform 6]: Secreted . |
| Tissue Expression | Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix. |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Prion disease;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules |
| Research Areas | |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains., |
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