Recombinant CD70 Fc-Fused Nanobody (VF0443)
Ucallm_WN0479
$365.00
Product details
Background:The protein encoded byThis gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation.This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
Specifications
| Size | 100μL |
| Target | CD70 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000; Flow Cyt 1-2μg/Test |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0164 |
| Immunogen | Purified recombinant Human CD70 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD70 protein. |
| Gene Name | CD70 CD27L CD27LG TNFSF7 |
| Protein Name | CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70) |
| Other Name | CD70; / CD27L; / CD27LG; / TNFSF7; / CD70 antigen; / CD27 ligand; / CD27-L; / Tumor necrosis factor ligand superfamily member 7; / CD antigen CD70; / CD70 nanobody |
| Species | Human |
| Gene ID | 970 |
| Uniprot | P32970 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type II membrane protein . |
| Tissue Expression | B-cell,Blood |
| Signaling_pathway | Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction |
| Research Areas | |
| Function | Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer., |
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