Repetin Polyclonal Antibody
Ucallm_WP14254-50
Price range: $268.00 through $328.00
Product details
Background:
domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats., function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase., similarity:Belongs to the S100-fused protein family., similarity:Contains 2 EF-hand domains., tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.,
Specifications
| Size | 50μL/100μL |
| Target | Repetin |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 90kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697 |
| Specificity | Repetin Polyclonal Antibody detects endogenous levels of Repetin protein. |
| Gene Name | RPTN |
| Protein Name | Repetin |
| Other Name | RPTN; / Repetin |
| Species | Human |
| Gene ID | 126638 |
| Uniprot | Q6XPR3, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P97347 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Expression | Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheath and in the filiform papilli of the tongue. |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats.,Function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase.,similarity:Belongs to the S100-fused protein family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue., |
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