SKU: WP14267 Categories: ,

RFX3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14267-100
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Product details

Background:

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013],

Specifications

Size50μL/100μL
TargetRFX3
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)84kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human RFX3. AA range:641-690
SpecificityRFX3 Polyclonal Antibody detects endogenous levels of RFX3 protein.
Gene NameRFX3
Protein NameTranscription factor RFX3
Other NameRFX3; / Transcription factor RFX3; / Regulatory factor X 3
SpeciesHuman
Gene ID5991
UniprotP48380,
Species.1Mouse
Gene ID.119726
Uniprot.1P48381
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionMuscle,Testis,
Signaling_pathway
Research Areas
FunctionFunction:Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.,similarity:Belongs to the RFX family.,
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