Price range: $268.00 through $328.00
Background:
This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016],
| Size | 50μL/100μL |
| Target | GARNL1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 223kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RGPA1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RALGAPA1 GARNL1 KIAA0884 TULIP1 |
| Protein Name | Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240) |
| Other Name | Ral GTPase-activating protein subunit alpha-1; / GAP-related-interacting partner to E12; / GRIPE; / GTPase-activating Rap/Ran-GAP domain-like 1; / Tuberin-like protein 1; / p240 |
| Species | Human |
| Gene ID | 253959 |
| Uniprot | Q6GYQ0, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6GYP7, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | O55007 |
| Cellular Localization | Cytoplasm . Nucleus . Translocated to the nucleus, when associated with TCF3/E12. . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Ras signaling pathway |
| Research Areas | >>Ras signaling pathway |
| Function | regulation of small GTPase mediated signal transduction, |
