Ribosomal Protein L10A Polyclonal Antibody
Ucallm_WP14292-50
Price range: $268.00 through $328.00
Product details
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes
Specifications
| Size | 50μL/100μL |
| Target | Ribosomal Protein L10A |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from Ribosomal Protein L10A . at AA range: 30-110 |
| Specificity | Ribosomal Protein L10A Polyclonal Antibody detects endogenous levels of Ribosomal Protein L10A protein. |
| Gene Name | RPL10A |
| Protein Name | 60S ribosomal protein L10a |
| Other Name | RPL10A; / NEDD6; / 60S ribosomal protein L10a; / CSA-19; / Neural precursor cell expressed developmentally down-regulated protein 6; / NEDD-6 |
| Species | Human |
| Gene ID | 4736 |
| Uniprot | P62906, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P53026, |
| Species.2 | Rat |
| Gene ID.2 | 81729 |
| Uniprot.2 | P62907 |
| Cellular Localization | nucleus,nucleolus,cytoplasm,cytosol,ribosome,focal adhesion,large ribosomal subunit,membrane,cytosolic large ribosomal subunit,extracellular exosome, |
| Tissue Expression | Breast,Cervix, |
| Signaling_pathway | |
| Research Areas | >>Ribosome; / >>Coronavirus disease - COVID-19 |
| Function | similarity:Belongs to the ribosomal protein L1P family., |
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