SKU: WP14295 Categories: ,

Ribosomal Protein L12 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14295-100
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Product details

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetRibosomal Protein L12
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)18kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human RPL12. AA range:61-110
SpecificityRibosomal Protein L12 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L12 protein.
Gene NameRPL12
Protein Name60S ribosomal protein L12
Other NameRPL12; / 60S ribosomal protein L12
SpeciesHuman
Gene ID6136
UniprotP30050,
Species.1Mouse
Gene ID.1269261
Uniprot.1P35979,
Species.2Rat
Gene ID.2499782
Uniprot.2P23358
Cellular Localizationnucleolus,cytosol,focal adhesion,membrane,cytosolic large ribosomal subunit,extracellular matrix,extracellular exosome,
Tissue ExpressionBrain,Epithelium,Ovary,
Signaling_pathway
Research Areas>>Ribosome; / >>Coronavirus disease - COVID-19
FunctionFunction:Binds directly to 26S ribosomal RNA.,similarity:Belongs to the ribosomal protein L11P family.,
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