Price range: $268.00 through $328.00
Background:
function:Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity., similarity:Belongs to the AROS family., subunit:Interacts with RPS19 (By similarity). Interacts with SIRT1., tissue specificity:Widely expressed (at protein level).,
| Size | 50μL/100μL |
| Target | Ribosomal Protein S19BP |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 15kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RPS19BP1. AA range:71-120 |
| Specificity | Ribosomal Protein S19BP Polyclonal Antibody detects endogenous levels of Ribosomal Protein S19BP protein. |
| Gene Name | RPS19BP1 |
| Protein Name | Active regulator of SIRT1 |
| Other Name | RPS19BP1; / AROS; / Active regulator of SIRT1; / 40S ribosomal protein S19-binding protein 1; / RPS19-binding protein 1; / S19BP |
| Species | Human |
| Gene ID | 91582 |
| Uniprot | Q86WX3, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8C6B9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleolus . |
| Tissue Expression | Widely expressed (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity.,similarity:Belongs to the AROS family.,subunit:Interacts with RPS19 (By similarity). Interacts with SIRT1.,tissue specificity:Widely expressed (at protein level)., |
