Product details
Background:
RIM1 rabbit pAb
Ucallm_WP6605-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | RIMS1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 186kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RIM1 |
| Specificity | This antibody detects endogenous levels of RIM1 at Human, Mouse,Rat |
| Gene Name | RIMS1 KIAA0340 RAB3IP2 RIM1 Nbla00761 |
| Protein Name | Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 2) |
| Other Name | |
| Species | Human |
| Gene ID | 22999 |
| Uniprot | Q86UR5, |
| Species.1 | Mouse |
| Gene ID.1 | 116837 |
| Uniprot.1 | Q99NE5, |
| Species.2 | Rat |
| Gene ID.2 | 84556 |
| Uniprot.2 | Q9JIR4 |
| Cellular Localization | Cell membrane; Peripheral membrane protein . Cell junction, synapse . Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein . |
| Tissue Expression | Expressed in melanocytes (PubMed:23999003). Detected in brain and retina (PubMed:23999003). |
| Signaling_pathway | Organismal Systems >> Nervous system >> Synaptic vesicle cycle |
| Research Areas | |
| Function | Rab effector involved in exocytosis (By similarity). May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (By similarity). Plays a role in dendrite formation by melanocytes . |
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