RL7A Polyclonal Antibody
Ucallm_WP0808-50
Price range: $268.00 through $328.00
Product details
Background:
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene t
Specifications
| Size | 50μL/100μL |
| Target | RL7A |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 29kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 180-260 |
| Specificity | RL7A Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RPL7A SURF-3 SURF3 |
| Protein Name | 60S ribosomal protein L7a (PLA-X polypeptide) (Surfeit locus protein 3) |
| Other Name | |
| Species | Human |
| Gene ID | 6130 |
| Uniprot | P62424, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P12970, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P62425 |
| Cellular Localization | nucleus,nucleolus,cytoplasm,cytosol,ribosome,cell-cell adherens junction,focal adhesion,membrane,cytosolic large ribosomal subunit,polysomal ribosome,extracellular exosome, |
| Tissue Expression | B-cell,Cerebellum,Eye,Lung,Placenta,Pooled,Skin,Uterus, |
| Signaling_pathway | |
| Research Areas | >>Ribosome; / >>Coronavirus disease - COVID-19 |
| Function | Disease:Chromosomal recombination involving RPL7A activates the receptor kinase domain of the TRK oncogene.,similarity:Belongs to the ribosomal protein L7Ae family., |
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